Updated More Research Validates COVID-19 Severity & Outcome Correlates with Vitamin D Levels

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Updated November 26, 2022

Kyle Becker, Becker News reports Nov 22, “on a ‘Nature.com’ article published in mid-November titled, ‘Association between vitamin D supplementation and COVID-19 infection and mortality’ as cause for concern for lockdown proponents…

Vitamin D deficiency has long been associated with reduced immune function that can lead to viral infection. Several studies have shown that Vitamin D deficiency is associated with increases the risk of infection with COVID-19. However, it is unknown if treatment with Vitamin D can reduce the associated risk of COVID-19 infection, which is the focus of this study. In the population of US veterans, we show that Vitamin D2 and D3 fills were associated with reductions in COVID-19 infection of 28% and 20%, respectively [(D3 Hazard Ratio (HR) = 0.80, [95% CI 0.77, 0.83]), D2 HR = 0.72, [95% CI 0.65, 0.79]]. Mortality within 30-days of COVID-19 infection was similarly 33% lower with Vitamin D3 and 25% lower with D2 (D3 HR = 0.67, [95% CI 0.59, 0.75]; D2 HR = 0.75, [95% CI 0.55, 1.04]). We also find that after controlling for vitamin D blood levels, veterans receiving higher dosages of Vitamin D obtained greater benefits from supplementation than veterans receiving lower dosages. Veterans with Vitamin D blood levels between 0 and 19 ng/ml exhibited the largest decrease in COVID-19 infection following supplementation. Black veterans received greater associated COVID-19 risk reductions with supplementation than White veterans. As a safe, widely available, and affordable treatment, Vitamin D may help to reduce the severity of the COVID-19 pandemic”.

The statistical analysis showed “Vitamin D3 supplementation was associated with a 33% lower risk of COVID-19 infection ending in mortality within 30 days,” the study noted. “However, results for vitamin D2 were statistically insignificant.”

Access the full article here

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January 19, 2022

A clinical study published in the Indian Journal of Clinical Practice, Vol. 32, No. 6, November 2021 reports patients with a vitamin D blood serum level of >30 ng/mL didn’t die at all.

In this smaller study, “the findings are still statistically significant and provide a strong indication that Vitamin D has the potential to save millions of lives with respect to any viral infection“. The study used eighty-one patients (18.5% were less than 40 years of age, 45% were 41-60 years, 35.8% more than 60 years of age) admitted to COVID wards and ICU with RT-PCR positive reports:

  • 21% had severe vitamin D deficiency
    • 64.7% patients required invasive mechanical ventilation
    • 76.47% patients died.
  • 33% had moderate vitamin D deficiency
  • 25% mild vitamin D deficiency
  • 21%  normal vitamin D level
    • All patients who had normal level of vitamin D were discharged from the hospital with only 1 patient requiring invasive mechanical ventilation

Findings included:

  1. “As the level of vitamin D increased from severely low to normal level, requirement of high oxygen support decreased and SpO2 at room air increased.
  2. Mean of vitamin D among the patients who died was 10.4963 while mean of vitamin D level among patients who survived and were discharged was 27.2362.
  3. Mean of serum ferritin and mean of interleukin (IL)-6 was high in patients who died and low in patients who were discharged”.

Conclusions: “Vitamin D level plays an important role in COVID-19 disease. Vitamin D have significant role in protection from severe form of disease”.

Access the complete study here

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