Antibody Response and Frequency of Covid-19 Infection 6 Months After COVID-19 Vaccination in Healthcare Workers

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May 15, 2022

Emerging Infectious Diseases reported in Medscape Nursing recent study results regarding antibody response in healthcare workers six months after Covid vaccination. The study concluded:

The study findings concluded: 

  • Antibodies induced by mRNA COVID-19 vaccination wane but remained detectable through 6 months after vaccination.
  • Significantly lower vaccine-induced antibodies against Delta compared to wild-type virus. Asymptomatic infections determined by NP seroconversions were relatively frequent, but symptomatic infection was rare, and severe disease was absent.
  • 1 of 17 unvaccinated persons have onset of severe COVID-19, versus no severe cases among 227 vaccinated participants.
  • Of vaccinated persons, 2 had symptomatic, PCR-proven breakthrough infections, both of which were managed as outpatient cases. We observed that 26% of vaccinated participants developed antibodies against SARS-CoV-2 NP, suggesting that vaccinated persons experienced exposures to SARS-CoV-2 as frequently as the unvaccinated population, yet rarely had onset of overt clinical disease.

Access the complete study here


 

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